Who Wins the Olympic Games: Economic Development and Medal Totals

This paper examines determinants of Olympic success at the country level. Does the U.S. win its fair share of Olympic medals? Why does China win 6% of the medals even though it has 1/5 of the world's population? We consider the role of population and economic development in determining medal totals from 1960-1996. We also provide out of sample predictions for the 2000 Olympics in Sydney.

l. suis medication of piglets with Baycoxo 5% against coccidiose and for stabilisation of the microflora against intestinal infections and reducing the application of antibiotica and vaccines against diarrhoea with E.coli and Clostridia

After the oral treatment of all p1glets 3 - 5 days after birth with Baycox 5% we found a better intestine health in the suckling and in the flatdeck period. ln this study there was a reduced diarrhoea dunng suckling and in the flatdeck.With the Baycox• therapeutic the vaccination program against E. coli and Clostridium perfringens Typ C and the application of antibiotica to the weaners could be decreased for nearly 40 % during the breeding period. AII pigs got better health status with higher weight gain and uniformity

Diffusion and dispersion of passive tracers: Navier-Stokes versus MHD turbulence

A comparison of turbulent diffusion and pair-dispersion in homogeneous, macroscopically isotropic Navier-Stokes (NS) and nonhelical magnetohydrodynamic (MHD) turbulence based on high-resolution direct numerical simulations is presented. Significant differences between MHD and NS systems are observed in the pair-dispersion properties, in particular a strong reduction of the separation velocity in MHD turbulence as compared to the NS case. It is shown that in MHD turbulence the average pair-dispersion is slowed down for $\tau_\mathrm{d}\lesssim t\lesssim 10 \tau_\mathrm{d}$, $\tau_\mathrm{d}$ being the Kolmogorov time, due to the alignment of the relative Lagrangian tracer velocity with the local magnetic field. Significant differences in turbulent single-particle diffusion in NS and MHD turbulence are not detected. The fluid particle trajectories in the vicinity of the smallest dissipative structures are found to be characterisically different although these comparably rare events have a negligible influence on the statistics investigated in this work.Comment: Europhysics Letters, in prin

Sources of dynamic variability in NF-κB signal transduction: a mechanistic model

The transcription factor NF-{kappa}B (p65/p50) plays a central role in the coordination of cellular responses by activating the transcription of numerous target genes. The precise role of the dynamics of NF-{kappa}B signalling in regulating gene expression is still an open question. Here, we show that besides external stimulation intracellular parameters can influence the dynamics of NF-{kappa}B. By applying mathematical modelling and bifurcation analyses, we show that NF-{kappa}B is capable of exhibiting different types of dynamics in response to the same stimulus. We identified the total NF-{kappa}B concentration and the I{kappa}B{alpha} transcription rate constant as two critical parameters that modulate the dynamics and the fold change of NF-{kappa}B. Both parameters might vary as a result of cell-to-cell variability. The regulation of the IκBα transcription rate constant, e.g. by co-factors, provides the possibility of regulating the NF-{kappa}B dynamics by crosstalk

Hysteresis phenomenon in turbulent convection

Coherent large-scale circulations of turbulent thermal convection in air have been studied experimentally in a rectangular box heated from below and cooled from above using Particle Image Velocimetry. The hysteresis phenomenon in turbulent convection was found by varying the temperature difference between the bottom and the top walls of the chamber (the Rayleigh number was changed within the range of $10^7 - 10^8$). The hysteresis loop comprises the one-cell and two-cells flow patterns while the aspect ratio is kept constant ($A=2 - 2.23$). We found that the change of the sign of the degree of the anisotropy of turbulence was accompanied by the change of the flow pattern. The developed theory of coherent structures in turbulent convection (Elperin et al. 2002; 2005) is in agreement with the experimental observations. The observed coherent structures are superimposed on a small-scale turbulent convection. The redistribution of the turbulent heat flux plays a crucial role in the formation of coherent large-scale circulations in turbulent convection.Comment: 10 pages, 9 figures, REVTEX4, Experiments in Fluids, 2006, in pres

A New Framework for Innovation-Based Regional Development

To foster sustainable regional development, many regions rely on innovations. To safeguard the generation of innovations and their market introduction, companies have increasingly used technology roadmapping and open innovation. The project INNOrural (Innovations for sustainable rural development) expanded these concepts by applying them to regions. This led to the rise of the “Regional Open Innovation Roadmapping” framework for innovation-based regional development (ROIR). This framework was tested by conducting two innovation roadmapping processes in the model region of Märkisch-Oderland (MOL), Germany: the certification of regional wood fuel and the establishment of a competence center for precision farming technology. Both innovation ideas were selected during the roadmapping process by applying a sustainability assessment. After 12 months, two complete roadmaps were ready for implementation. Key principles of ROIR were identified, including the use of a clear and replicable sustainability assessment method, the involvement of all relevant stakeholder groups in the early process and the cooperation between regional and subject experts. Generally, the broader adaptation of ROIR for additional regions will be useful. Nevertheless, the ROIR processes need to be evaluated in depth to develop a better understanding and to provide evidence of the benefits and limitations of this approach

The extostosin family: Proteins with many functions

Heparan sulfates are complex sulfated molecules found in abundance at cell surfaces and in the extracellular matrix. They bind to and influence the activity of a variety of molecules like growth factors, proteases and morphogens and are thus involved in various cell–cell and cell–matrix interactions. The mammalian EXT proteins have glycosyltransferase activities relevant for HS chain polymerization, however their exact role in this process is still confusing. In this review, we summarize current knowledge about the biochemical activities and some proposed functions of the members of the EXT protein family and their roles in human disease.publishedVersio

Nonlinear Competition Between Small and Large Hexagonal Patterns

Recent experiments by Kudrolli, Pier and Gollub on surface waves, parametrically excited by two-frequency forcing, show a transition from a small hexagonal standing wave pattern to a triangular ``superlattice'' pattern. We show that generically the hexagons and the superlattice wave patterns bifurcate simultaneously from the flat surface state as the forcing amplitude is increased, and that the experimentally-observed transition can be described by considering a low-dimensional bifurcation problem. A number of predictions come out of this general analysis.Comment: 4 pages, RevTex, revised, to appear in Phys. Rev. Let

Defect Chaos of Oscillating Hexagons in Rotating Convection

Using coupled Ginzburg-Landau equations, the dynamics of hexagonal patterns with broken chiral symmetry are investigated, as they appear in rotating non-Boussinesq or surface-tension-driven convection. We find that close to the secondary Hopf bifurcation to oscillating hexagons the dynamics are well described by a single complex Ginzburg-Landau equation (CGLE) coupled to the phases of the hexagonal pattern. At the bandcenter these equations reduce to the usual CGLE and the system exhibits defect chaos. Away from the bandcenter a transition to a frozen vortex state is found.Comment: 4 pages, 6 figures. Fig. 3a with lower resolution no